Rodriguez CM*, Wright SE*, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans A, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, Todd PK (2019) A native function for CGG RAN translation in regulated Fragile X protein synthesis. Nature Neuroscience, in press
*equal contribution

Green KM, Sheth U, Flores BN, Wright SE, Sutter A, Kearse MG, Barmada S, Ivanova MI, Todd PK. (2019) High-throughput screening yields several small molecule inhibitors of repeat-associated non-AUG translation. Journal of Biological Chemistry, in press

Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. (2019) Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes & Development, 33(13-14): 871-885. PMID: 31171704
•Recommended by F1000

Li Z, Kearse MG, Huang C. (2018) The nuclear export of circular RNAs is primarily defined by their length. RNA Biology, 6(1): 1-4. PMID: 30526278

Mageeney CM*, Kearse MG*, Gershman BW, Pritchard CE, Colquhoun JM, Ware VC. (2018) Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster. Fly, 12(3-4):143-163. PMID: 30465696
*equal contribution

Green KM, Glineburg MB*, Kearse MG*, Flores B, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada S, Todd PK. (2017) RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications, 8(1): 2005. PMID: 29222490
*equal contribution

Kearse MG, Wilusz JE. (2017) Non-AUG translation: a new start for protein synthesis in eukaryotes. Genes & Development, 31(17): 1717-1731. PMID: 28982758

Kearse MG, Green KM, Krans A, Rodriquez CM, Linsalata AE, Goldstrohm AC, Todd PK. (2016) CGG Repeat-associated non-AUG translation utilizes a cap-dependent, scanning mechanism of initiation to produce toxic proteins. Molecular Cell, 62(2): 314-322. PMID: 27041225
•Previewed in Molecular Cell, 62(2): 155-156
•Highlighted in Nature Reviews Molecular Cell Biology, 17: 264

Krans A, Kearse MG, Todd PK. (2016) Repeat associated non-AUG translation from antisense CCG repeats in Fragile X Tremor/Ataxia. Annals of Neurology, 80(6): 871-881. PMID: 27761921

Kearse MG, Todd PK. (2014) RAN translation and its impact in neurodegenerative disease. Neurotherapeutics, 11(4): 721-731. PMID: 25005000

Fischl MJ, Weimann SR, Kearse MG, Burger RM. (2014) Slowly emerging glycinergic transmission enhances inhibition in the sound localization pathway of the avian auditory system. J Neurophysiol, 111(3): 565-572. PMID: 24198323

Kearse MG, Ireland JA, Prem SM, Chen AS, Ware VC. (2013) RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes. Nucleus, 4(3): 241-258. PMID: 23778934
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Gatto GJ Jr, Ao Z, Kearse MG, Zhou M, Morales CR, Daniels E, Bradley BT, Goserud MT, Goodman KB, Douglas SA, Harpel MR, Johns DG. (2013) NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation. J Enzyme Inhib Med Chem, 28(1): 95-104. PMID: 22136506

Kearse MG, Chen AS, Ware VC. (2011) Expression of ribosomal protein L22e family members in Drosophila melanogaster: rpL22-like is differentially expressed and alternatively spliced. Nucleic Acids Res, 39(7): 2701-2716. PMID: 21138957