• The last bit of Mike’s postdoc work in Peter Todd’s lab describing how RAN translation at CGG repeats regulates FMRP synthesis is accepted at Nature Neuroscience !
• Kenzie Bevins and Daisy DiVita join us for a first-year rotation. Welcome!
• Collaborative work with Katelyn Green from Peter Todd’s lab using high-throughput screening to identify potential inhibitors of neuropathogenic RAN translation is accepted at JBC.
• After 2.5 months of cleaning, ordering, organizing, a safety inspection, and IBC approval, the lab starts running experiments…first with a humble (and successful) PCR reaction.
• The lab’s last piece of major equipment—a new fully-automated Biocomp piston fractionator and flow cell with all the bells and whistles—arrives (coincidentally on Mike's birthday). We are ready for ribosome and polysome profiling!
• Our new, top-of-the-line GloMax Discover multimode microplate reader arrived. It’s capable of it all—UV/Vis absorbance, fluorescence, luminescence, FRET, BRET—and ready for collaborations.
• The lab is now part of the Molecular, Cellular, and Developmental Biology (MCDB) PhD program.
• The lab is awarded an R00 grant from the NIH to study aberrant translation initiation from atypical start codons!! We are really excited about where this work will take us.
• The lab joins the Biomedical Sciences Graduate Program (BSGP).
• Mike’s recent paper in Genes and Development describing how non-AUG translation can be resistant to potent protein synthesis inhibitors is recommended by F1000.
• Mike and family arrive to Columbus. Recruitment for the initial lab members begins. Exciting things to come.
• The lab joins the Ohio State Biochemistry Program (OSBP) and Mike is now a mentoring faculty for PhD students in the program.
• The lab is now an active member of the Center for RNA Biology.
• The Kearse lab officially opens…from afar…until Mike moves from Philly later this month.